The relation between maternal obesity and placenta accreta spectrum: A multinational database study

Introduction It has been suggested that women with obesity have increased risk of developing placenta accreta spectrum (PAS). is unclear if this independent the cesarean delivery seen itself. The aim study was to explore association between maternal and PAS, particularly severe PAS (percreta). Material methods This a cohort based on cases recorded in International Society for Placenta Accreta Spectrum (IS-PAS) database April 2008 May 2019. Multivariable logistic regression used effect severity PAS; model adjusted other known factors including previous deliveries, age, previa. estimated rate hypothetical similar characteristics (previous same parity) calculated compared observed (one sample test proportions). Results Of 386 included 227 (58.8%) had disease In univariable analysis, initially appeared be associated odds most type percreta (odds ratio [OR] 1.87; 95% CI 1.14-3.09); however, lost after adjustment (OR 1.44; 0.85-2.44). There no difference from alone (31.3% vs 36.8%, respectively; P = .07). Conclusions Obesity does not seem an factor or PAS. These findings are relevant clinicians provide accurate counseling regarding risks related pregnancy.